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Nov 13, 2025 · Complete information for CD37 gene (Protein Coding), CD37 Molecule, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternate splicing results in multiple transcript variants encoding different isoforms. [6]
May 15, 2024 · CD37 is a cell-surface glycoprotein that belongs to the four-transmembrane tetraspanin superfamily, 17 known to interact with a range of adhesion molecules, growth and signaling receptors, as well as ot...
Jul 18, 2025 · Cancer cells evade the immune system by disrupting phagocytic clearance. Here, the authors identify CD37 as a potential checkpoint molecule expressed on non-phagocytes and propose that binding to ...
Aug 6, 2024 · CD37主要表达于成熟B淋巴细胞表面，作为治疗B细胞淋巴瘤的重要靶点进行开发。 最近的研究显示，CD37-CAR-T细胞能够在体内高效特异性杀伤急性髓系白血病（acute myeloid leukemia，AML）细胞，分泌促炎细胞因子，并在体内控制癌症进展，同时具有更低的瘤外毒性 ...
Jun 18, 2024 · Acute myeloid leukemia (AML) is characterized by the accumulation of immature myeloid cells in the bone marrow and the peripheral blood. Nearly half of the AML patients relapse after standard induction ...
