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Apr 1, 2001 · Chromosomal rearrangements involving chromosome bands 12q13–15 are very frequent findings in benign solid tumors, and recently, the primary molecular target for these aberrations was identified as the ge...
HMGIC, the gene for an architectural transcription factor, is ampli®ed and rearranged in a subset of human sarcomas Jeanne-Marie Berner1, Leonardo A Meza-Zepeda1, Patrick FJ Kools2, Anne Forus1 ...
Comparisons between HMGIC gene expression in tumor samples from 11 uterine leiomyomata and 7 normal matched myometrium or in vitro cell cultures (chorionic villi, placenta, myometrium, leiomyoma, and skin) were also p...
HMGIC的基因组组织应进一步加深我们对12q14-q15区域的了解，在该区域还绘制了其他间充质来源的肿瘤。 "点击查看英文标题和摘要"
Dec 19, 2024 · 这种基因叫HMGIC，它的作用是当摄入的营养过剩时，在动物体内产生更多的储存脂肪的细胞，从而导致发胖，据此，研究人员培育出了HMGIC存在缺陷的实验鼠，结果发现，这种HMGIC的缺陷的实验鼠，即使吃得很多，体内储存脂肪的细胞也不会增加，体重仍保持正常。
Jan 15, 1996 · HMGIC, a member of the HMGI family of high mobility group proteins, is disrupted in 3/3 lipomas characterized by 12q14–q15 rearrangements. To define the genomic structure of the HMGIC gene, YACs from th...
Sep 14, 1999 · Differential expression of HMGIC mRNA isoforms In order to investigate whether the expression of alternative HMGIC mRNA transcripts was subject to regulation, two differentiation models were studied.
Sep 9, 1999 · Abstract The HMGIC gene has been implicated in the control of cell proliferation and development. We show here that HMGIC has multiple mRNA isoforms that arise by transcription initiation from alternativ...
Oct 1, 1996 · Recently the high-mobility group protein gene HMGIC has been found to be rearranged in a variety of benign mesenchymal tumors with 12q13–q15 aberrations, such as angiomyxoma, fibroadenomas of the breast,...
Comparisons between HMGIC gene expression in tumor samples from 11 uterine leiomyomata and 7 normal matched myometrium or in vitro cell cultures (chorionic villi, placenta, myometrium, leiomyoma, and skin) were also p...
