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Jan 15, 2026 · WNT4 (Wnt Family Member 4) is a Protein Coding gene. Diseases associated with WNT4 include 46,Xx Sex Reversal With Dysgenesis Of Kidneys, Adrenals, And Lungs and Mullerian Aplasia And Hyperandrogenism.
WNT4 is a secreted protein that, in humans, is encoded by the WNT4 gene, found on chromosome 1. [5][6] It promotes female sex development and represses male sex development. Loss of function may have consequences, suc...
Oct 12, 2021 · WNT family member 4 (WNT4), which belongs to the conserved WNT protein family, plays an important role in the development and differentiation of many cell types during the embryonic development ...
Dec 22, 2024 · WNT4基因的功能 WNT4 基因是Wnt家族的一员,这个家族的基因在生物体的发育过程中扮演着至关重要的角色。WNT4基因编码的蛋白质是一种分泌性糖蛋白,主要参与调控性腺发育和性别决定。
Wnt 家族成员 4: Wnt 基因家族由编码分泌信号蛋白的结构相关基因组成。这些蛋白质与肿瘤发生和几个发育过程有关,包括胚胎发生过程中细胞命运和模式的调节。该基因是 Wnt 基因家族的成员,是第一个显示影响性别决定级联的信号分子。它编码的蛋白质与小鼠和大鼠的 Wnt4 蛋白质具有 98% 的氨基酸 ...
The WNT4 gene belongs to a family of WNT genes that play critical roles in development before birth. Learn about this gene and related health conditions.
WNT4 (Wingless-related MMTV integration site 4) WNT4 is a signaling molecule that regulates ovarian development and antagonizes testis formation. Wnt4 knockout in XY mice causes abnormal vasculature and function, whil...