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Jan 14, 2026 · Complete information for APOA5 gene (Protein Coding), Apolipoprotein A5, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
APOA5 mainly functions to influence plasma triglyceride levels. [16] The first suggested mechanism supposes that APOA5 functions as an activator of lipoprotein lipase (which is a key enzyme in triglyceride catabolism)...
Dec 24, 2024 · APOA5基因的基本信息 APOA5基因，全称为apolipoprotein A5，位于人类染色体11q23.3位置。这个基因编码一种蛋白质，属于Apolipoproteins家族，也被称为RAP3或APOA-V。通过OMIM编号606368、Ensembl编号ENSG00000110243和UniProt编号Q6Q788，我们可以追踪到更多关于APOA5的详细信息。
ApoA5 loss-of-function single nucleotide polymorphisms are associated with reduced lipolysis, poor remnant clearance and concomitantly, hypertriglyceridemia. Although there have been substantial breakthroughs in under...
Mar 11, 2015 · The APOA5*2 haplotype, which consists of 3 SNPs (see 606368.0004), is present in approximately 16% of Caucasians and is associated with increased plasma triglyceride concentrations (Pennacchio et al., 2...
载脂蛋白 A5： 该基因编码的蛋白质是一种载脂蛋白，在调节血浆甘油三酯水平方面发挥着重要作用，而血浆甘油三酯水平是冠状动脉疾病的主要危险因素。它是高密度脂蛋白的组成部分，与大鼠蛋白高度相似，在肝损伤时上调。该基因的突变与高甘油三酯血症和 5 型高脂蛋白血症有关。该基因位于 ...
APOA5 is defined as an apolipoprotein predominantly expressed in the liver that regulates triglyceride-rich lipoprotein (TRL) metabolism, lowering plasma triglycerides by stimulating lipoprotein lipase-dependent hydro...
