m.baidu.com
凋亡相关颗粒样蛋白（Asc）｜Elisa指标 - 百度
定义：凋亡相关颗粒样蛋白（apoptosis - associated speck - like protein containing a CARD，ASC）也被称为 PYCARD，是一种在细胞凋亡和炎症反应过程中发挥关键作用的蛋白质。它作为一种接头蛋白，能够连接不同的信号分子，促进细胞内信号通路的传导。
asc基因
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www.genecards.org
PYCARD Gene - GeneCards | ASC Protein | ASC Antibody
PYCARD is a protein coding gene that encodes ASC, a key mediator in apoptosis and inflammation. It has two domains, PYD and CARD, that interact with caspase and other proteins in various signaling pathways.
actamicro.ijournals.cn
炎性小体中ASC斑点形成机理及调控机制
Cai等研究者利用基因和生物化学的方法发现NLRP3和AIM2的激活剂可以使ASC在酵母菌中形成朊蛋白，进一步研究表明含有PYD结构域的ASC重组体可以形成朊蛋白样纤维聚合，将非活化的ASC转变成为活化的朊蛋白，这对下游的免疫、炎症信号通路非常关键。
lifescience.sinh.ac.cn
PDF 凋亡相关斑点样蛋白的研究进展
本文介绍了凋亡相关斑点样蛋白(ASC)的发现、结构特点和功能机制,以及它在炎症、肿瘤、细胞凋亡和NF-κB信号通路中的作用。ASC是一种含有PYD和CARD两个结构域的接头分子,可以通过寡聚化募集并激活与其同源结构域的其他蛋白,参与多条信号转导途径。
pmc.ncbi.nlm.nih.gov
Asc-1, PAT2 and P2RX5 are novel cell surface markers for white, beige ...
White, beige and brown adipocytes are developmentally and functionally distinct but often occur mixed together within individual depots. To target white, beige and brown adipocytes for diagnostic or therapeutic purpos...
www.sohu.com
凋亡相关颗粒样蛋白（ASC）｜ELISA指标_炎症_细胞_反应
定义：凋亡相关颗粒样蛋白（apoptosis - associated speck - like protein containing a CARD，ASC）也被称为 PYCARD，是一种在细胞凋亡和炎症反应过程中发挥关键作用的蛋白质。它作为一种接头蛋白，能够连接不同的信号分子，促进细胞内信号 ...
www.nature.com
ASC specks as a single-molecule fluid biomarker of ... - Nature
Lobanova et al. developed a single-molecule immunoassay for quantitative measurements of ASC specks in human biofluids. The authors discovered the combination of ASC speck with neurodegenerative ...
www.bafang.org.cn
Slc7a10基因的功能与作用机制解析 - 八方基因
SLC7A10基因概述 SLC7A10基因，也被称为asc-1，是 溶质载体家族7（Solute Carrier Family 7） 的成员之一。这个基因位于人类染色体19q13.11位置，编码一种蛋白质，主要负责氨基酸的转运。具体来说，SLC7A10主要参与 胱氨酸（cystine）和谷氨酸（glutamate）的转运，这两种氨基酸在细胞内外交换中起着关键作用。
en.wikipedia.org
ASCL1 - Wikipedia
Achaete-scute homolog 1 is a protein that in humans is encoded by the ASCL1 gene. [5][6] Because it was discovered subsequent to studies on its homolog in Drosophila, the Achaete-scute complex, it was originally named...
link.springer.com
Comprehensive review of ASC structure and function in immune ...
Besides cancer, ASC also plays a central role in sensing, regulation, and/or disease progression in bacterial infections, viral infections and in varied inflammatory diseases. ASC is expressed in different types of im...