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Feb 28, 2020 · The alanine-serine-cysteine transporter (referred to as SLC7A10 or Asc-1) is the light chain of the heterodimer amino acid transporter (HAT), and is a Na + -independent antiporter distributed ...
Jan 2, 2025 · 本文将详细介绍SLC7A10基因的功能、作用机制、信号通路以及与疾病的关系，帮助读者全面理解这一基因在人体中的重要角色。
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Feb 8, 2025 · The amino acid transporter ASC-1 is a white adipocyte-specific cell surface protein. ASC1 is a target for ufmylation and that UFBP1 is an essential component for ASC1 ufmylation. In conclusion, SLC7A10 h...
Jan 15, 2026 · SLC7A10 (Solute Carrier Family 7 Member 10) is a Protein Coding gene. Diseases associated with SLC7A10 include Cystinuria and Hyperekplexia. Among its related pathways are Transport of inorganic cations...
激活信号协整子 1 复杂亚基 1： 该基因编码激活信号协整合子 1 (ASC-1) 复合体的一个亚基。 ASC-1 复合物是一种转录共激活因子，在多种转录因子的基因反式激活中起重要作用，包括激活蛋白 1 (AP-1) 、核因子 kappa-B (NF-kB) 和血清反应因子 (SRF) 。编码的蛋白质包含一个 N 端 KH 型 RNA 结合基序，这是 ASC-1 ...
Asc型氨基酸转运蛋白1（ASC1），也被称为溶质载体家族7成员10（SLC7A10），是由SLC7A10基因编码的蛋白质。它与4F2HC结合，介导 D-丝氨酸和其他几种中性氨基酸的高亲和力转运。它可能通过在谷氨酸能突触处动员 D-丝…
Our data together with the patient history show that human Asc-1 represents a novel rare candidate gene for human hyperekplexia. However, the accompanying developmental delay in this proband also likely reflects the r...
Dec 18, 2024 · 基因的功能 SLC7A10编码的蛋白质主要负责细胞内氨基酸的转运。具体来说，它可能参与了中性氨基酸的跨膜运输，这对于细胞的正常生理功能至关重要。例如，它在神经元中的表达可能与神经递质的合成和释放有关。
The alanine-serine-cysteine transporter Asc-1 regulates the synaptic availability of D-serine and glycine (the two co-agonists of the NMDA receptor) and is regarded as an important drug target. To shuttle the substrat...
