Searching…
Nov 10, 2025 · GeneCards®: The Human Gene Database GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes. The knowledgebase a...
KEGG is a database resource for understanding high-level functions and utilities of biological systems, such as cells, organisms, ecosystems and the biosphere from molecular-level information, especially large-scale m...
Polymorphisms in the gene encoding methylenetetrahydrofolate reductase (MTHFR) have been investigated as risk factors for microvascular complications of diabetes; however, simultaneous analysis of these polymorphisms ...
View Gene Facts TRK-CTT7-1 (HGNC:35098) HGNC Entrez GeneReviews LOVD LSDB ClinVar tRNA-Lys (anticodon CTT) 7-1 non-coding RNA RNA, transfer TRNAL48, TRNAQ49P tRNA-Lys-CTT-7-1 0 0 No 1p36.13 GRCh37/hg19: chr1:16879957-...
高同型半胱氨酸(hyperhomocysteine,hHcy)血症已成为导致高血压、动脉粥样硬化、高脂血症、脑卒中等心脑血管疾病独立的危险因子。研究发现,亚甲基四氢叶酸还原酶(MTHFR)的编码基因发生突变会引起该酶活性下降,是导…
Feb 1, 2013 · MAGE-C1/CT7 is the most frequently expressed CT antigen in MM lesions being found in >50% of cases. 6, 7 We have described previously that CT7 is able to elicit a specific humoral immune response ...
研究显示，MAGE-C1/CT7在88.5%的MM患者骨髓细胞中高表达并与不良预后相关。通过 RNA干扰技术 沉默该基因，可抑制MM细胞增殖并 ...
Hepatocellular carcinoma is one of the most common malignant tumors and has caused a huge economic and healthy burden for a long time around the world. According to data released by the American Cancer Society in 2021...
Mar 18, 2024 · Sirtuin蛋白是一类从古细菌到人类高度保守的去乙酰化酶。 Sirtuin蛋白 的酶活依赖辅酶因子β-烟酰胺腺嘌呤二核苷酸NAD +，是通过热量限制延缓衰老策略的重要靶点，在多个物种中发挥着寿命调控的相关功能，被称为“长寿蛋白家族”。人类sirtuin家族的7个成员（SIRT1-7）均具有NAD + 结合和相对保守的 ...
来自南京医科大学的研究人员报告称，他们在19种 癌症 类型中系统鉴别了呈肿瘤—睾丸 (Cancer-testis,CT)基因表达模式的基因。他们的研究成果发布在1月27日的《自然通讯》（Nature Communications）杂志上。 南京医科大学的 胡志斌 (Zhibin Hu)教授、沙家豪（Jiahao Sha）教授和沈洪兵（Hongbing Shen）是这篇论文的 ...
