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Jul 17, 2025 · Complete information for CIRBP gene (Protein Coding), Cold Inducible RNA Binding Protein, including: function, proteins, disorders, pathways, orthologs, and expression.
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. [5][6][7] The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confr...
Oct 29, 2025 · 其体内的冷诱导 RNA 结合蛋白 CIRBP，表达量是人类的 3-5 倍，既能精准修复断裂的 DNA 双链，又能减少基因突变，甚至在果蝇身上复刻这种蛋白，还能延长寿命、提升抗辐射能力。
This study reports that cold-inducible RNA-binding protein (CIRBP) is a newly identified key regulator in DNA double-strand break (DSB) repair. Crystal structure of the hnRNP A18 RNA recognition motif has been reported.
Feb 22, 2024 · Cold-inducible RNA binding protein (CIRBP), a stress response protein, protects cells from mild hypothermia or hypoxia by stabilizing specific mRNAs and promoting their translation.
Jan 2, 2025 · 本文将详细介绍CIRBP基因的功能、作用机制、信号通路及其与疾病的关系，帮助读者全面理解这一重要的RNA结合蛋白。 CIRBP基因概述 CIRBP，全称cold inducible RNA binding protein ，中文名为冷诱导RNA结合蛋白，位于人类染色体19p13.3位置。
冷诱导型 RNA 结合蛋白： 启用 mRNA 3'-UTR 结合活性和核糖体小亚基 rRNA 结合活性。 参与 mRNA 稳定；翻译的积极调节；和对紫外线的反应。 位于细胞质和核质中。 [由基因组资源联盟提供，2022 年 4 月]
CIRBP的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为无
Cirbp基因具有聚 (U)RNA结合活性和翻译抑制活性，参与应激颗粒组装，调控细胞生长和细胞周期。 页面提供物种序列对比、转录本、蛋白质互作及表达量数据。
Cold-inducible RNA-Binding Protein (CIRBP) is a general stress-response factor in vertebrates harboring two domains: an RNA-recognition motif and a regulatory domain rich in RG/RGG motifs.
