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Jan 14, 2026 · Complete information for CNTN6gene (Protein Coding), Contactin 6, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Contactin 6 ... Contactin 6 is a protein in humans that is encoded by the CNTN6gene. [4] The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-ancho...
Dec 19, 2024 · 本文将详细介绍CNTN6基因的功能、作用机制、信号通路及其与疾病的关系，帮助读者全面了解这一重要基因。 CNTN6基因概述 CNTN6 ，也被称为NB-3 ，是一个位于3p26.3的基因，编码一种蛋白质产品。
Clinical investigations of the patients carrying CNTN5 or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway.
CNTN6主要在大脑皮层、海马和小脑中表达，尤其在神经元轴突和突触部位富集，其功能涉及神经元迁移、轴突导向和突触可塑性。 CNTN6通过与配体如受体蛋白酪氨酸磷酸酶（RPTP）结合，激活下游信号通路（如Fyn激酶），调控神经网络的精确连接。
Relevance to Autism A de novo duplication of the CNTN6gene was identified in an autistic proband from a simplex family (van Daalen et al., 2011).
关于 Cntn6 功能概要 Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within positive regulation of Notch signaling pathway. Located in parallel fiber to Purkinje cell synapse and plasma membrane...
