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GLI1 Gene - GeneCards | GLI1 Protein | GLI1 Antibody
Jan 15, 2026 · GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Polydactyly, Postaxial, Type A8 and Polydactyly, Preaxial I. Among its related pathways are Signaling by H...
en.wikipedia.org
GLI1 - Wikipedia
Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from human glioblastoma cells.
pmc.ncbi.nlm.nih.gov
Gli Proteins: Regulation in Development and Cancer - PMC
In mammals, they are represented by three proteins: Gli1, Gli2 and Gli3. Gli1 acts principally as a transcriptional activator, whereas Gli2 and Gli3 display both activator and repressor functions [15, 16, 17]. In the ...
zhuanlan.zhihu.com
Hedgehog 信号通路与癌症 | MedChemExpress - 知乎
根据其调节机制，非典型 Hh 信号转导主要分为三种类型：I 型、II 型和 III 型。 I 型由 Ptch 介导的信号转导：包括 IA 型 (Ptch 通过募集促凋亡因子如 caspase-9, DRAL, TUCAN 介导细胞凋亡) 和 IB 型 (Ptch 通过与细胞周期蛋白 cyclin B1 相互作用介导的细胞周期调节)。
www.ptgcn.com
GLI1 antibody (66905-1-Ig) | Proteintech | 武汉三鹰生物技术有限公...
GLI1, also known as Glioma-associated oncogene, is a 1106 amino acid protein, which belongs to the GLI C2H2-type zinc-finger protein family. GLI1 is detected in testis and Also expressed in the brain with highest expr...
www.bafang.org.cn
GLI1基因的功能与作用机制解析 - 八方基因
Jan 4, 2025 · 本文将详细介绍GLI1基因的功能、作用机制、信号通路及其与疾病的关系，帮助读者全面了解这一重要的基因。 GLI1基因概述 GLI1基因，全称为GLI family zinc finger 1，位于人类染色体12q13.3位置。 这个基因编码一种蛋白质，属于锌指蛋白家族中的C2H2类型。
www.medchemexpress.cn
GLI 家族锌指 1（GLI1）基因 | MCE
GLI 家族锌指 1： 该基因编码锌指蛋白 Kruppel 家族的一个成员。 编码的转录因子被 sonic Hedgehog 信号转导级联激活并调节干细胞增殖。 该蛋白的活性和核定位在抑制环中受 p53 的负调控。 已发现该基因编码不同异构体的多个转录变体。 [RefSeq 提供，2009 年 5 月]