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The human protein interleukin-2 receptor subunit alpha is encoded by a gene called IL2RA with a length around 51,6 kb. Alternative names for this protein coding gene are IL2R, IDDM10 and TCGFR. Location of IL2RA in hu...
Aug 7, 2023 · Here we show that both wild-type (IL-2 wt) and IL-2Rβγ-attenuated (IL-2 α-bias) agonists that preserve IL-2Rα (CD25) activities can effectively expand tumor-specific CD8 + T cells...
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity ...
Elevated levels of soluble IL-2Ra/CD25 may also have clinical and prognostic significance in patients with various lymphomas.
Nov 13, 2025 · IL2RA is a protein coding gene that encodes the interleukin 2 receptor alpha chain, involved in immune regulation and autoimmunity. Learn about its aliases, disorders, pathways, products, variants, and ...
The IL2RA gene is composed of eight exons and encodes the α chain of the IL-2 receptor complex (also known as CD25). IL2RA is central to immune regulation as an important modulator of immunity.
