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Myc - Wikipedia
The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the...
pmc.ncbi.nlm.nih.gov
The MYC oncogene — the grand orchestrator of cancer growth and...
MYC has two paralogues: MYCL and MYCN. The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small-cell lung cancer and N-MYC ...
www.genecards.org
MYC Gene - GeneCards | MYC Protein | MYC Antibody
Jan 15, 2026 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit. Among its relate...
www.nature.com
MYC in cancer: from undruggable target to clinical trials
Feb 19, 2025 · This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials.
www.intechopen.com
MYC: Master Regulator of Cell Death and Tumor Progression
Mar 14, 2025 · MYC gene has become one of the most investigated oncogenes for regulating programmed cell death and tumor growth. MYC is a transcription factor that regulates the expression of numerous genes involved i...
www.sciencedirect.com
Myc - an overview | ScienceDirect Topics
The myc family includes four transcription factors, c-myc, N-myc, L-myc, and S-myc, involved in the control of cell growth, differentiation, and apoptosis (69).
link.springer.com
Targeting MYC in T-Cell lymphoma via epigenetic modulation ... -...
6 days ago · Taken together, we identified LATC as an epigenetic agent by dually targeting post-transcriptional YBX1/ MYC mRNA stability and transcriptional p300/H4K16 lactylation to inhibit MYC-driven T-cell lymphoma...
perspectivesinmedicine.cshlp.org
MYC and the Pathway to Cancer - CSHL P
Even so, there is still a great deal, much of it fundamental, to learn about the function of MYC in both normal and neoplastic cells. MYC encodes a master transcription factor that dimerizes with MAX to control divers...
www.frontiersin.org
MYC: there is more to it than cancer - Frontiers
Mar 6, 2024 · MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular prolifera...
pmc.ncbi.nlm.nih.gov
MYC: there is more to it than cancer - PMC
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, differen...