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This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription c...
Complete information for MSX1 gene (Protein Coding), Msh Homeobox 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
The MSX1 gene is part of a larger family of homeobox genes, which control the formation of many body structures during early development. Specifically, this gene is critical for the normal development of the teeth and...
Ivens et al. (1990) found that the MSX1 gene maps to chromosome 4p16.1, slightly proximal to the HD locus (143100). This region shows homology of synteny with part of mouse chromosome 5 where the murine Msx1 gene is l...
More about the Msx1 gene Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity.
Explore the MSX1 gene, a crucial homeobox gene involved in embryonic development, particularly tooth, craniofacial, and limb formation. Learn about its role in various developmental disorders and its significance in research.
About this gene This gene has 2 transcripts (splice variants), 128 orthologues, 1 paralogue and is associated with 11 phenotypes.
MSX1 is defined as a DNA-binding protein encoded by a gene located on chromosome 4, which interacts with transcription factors to regulate gene expression essential for the initiation of tooth development.
Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Assigned HPA protein class (es) for the encoded protein (s).
We examine recent research findings, including studies on Msx1 mutations, signaling pathways, and gene-environment interactions, to elucidate the complex relationship between Msx1 and cleft palate.
