Plant Cell | 研究揭示植物病原细菌效应蛋白激活宿主抗性的机制!
革兰氏阴性植物病原细菌将专门的蛋白质(效应蛋白)注入其宿主体内,以中和防御并操纵宿主的代谢,使 病原体 生存。 当宿主的抗性(R)蛋白识别转运的细菌效应蛋白时,防御反应就开始了。
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革兰氏阴性植物病原细菌将专门的蛋白质(效应蛋白)注入其宿主体内,以中和防御并操纵宿主的代谢,使 病原体 生存。 当宿主的抗性(R)蛋白识别转运的细菌效应蛋白时,防御反应就开始了。
通过质谱分析RPM1蛋白复合物,以及利用反向遗传学方法检测Rop类G蛋白家族成员对RPM1功能的影响,可以发现更多参与RPM1信号转导的蛋白,进而从其功能阐明RPM1信号起始机制。
Therefore, we undertook a detailed structure-function analysis of RPM1 using both stable transgenic Arabidopsis and the heterologous N. benthamiana transient expression system. We found that immune signaling is induce...
Jan 3, 2021 · RPM1- and RPS2-mediated plant defense response induced by RIN4. a AvrB or AvrRpm1 targets RIN4 and induces RIPK-mediated phosphorylation of RIN4, which, in turn, leads to the activation of RPM1 and induc...
Aug 29, 2017 · Our results reveal an additive effect of hydrophobic conserved residues in the CC domain for RPM1 function and RPM1 self-association and their necessity for RPM1-RIN4 interaction.
Aug 19, 2025 · 这一发现不仅解答了关于RPM1作用机制的长期疑问,也揭示了植物NB-LRR蛋白信号转导机制的多样性。 与那些需要在激活后进入细胞核的NB-LRR蛋白(如MLA、RPS4)不同,RPM1代表了一类在特定亚细胞区室“就地”完成免疫监控和信号启动的“哨兵”。
植物免疫受体蛋白RPM1在细胞膜上感知RIN4的磷酸化而被激活,引起植物超敏反应和抗病性。 最近研究证明激活后的RPM1是在细胞膜上起始信号转导的,但其分子机制仍不清楚。
The intrinsically disordered structural platform of the plant defence hub protein RPM1-interacting protein 4 provides insights into its mode of action in the host-pathogen interface and evolution of the nitrate-induce...
Oct 4, 2021 · In this study, we showed that RPM1-INDUCED PROTEIN KINASE (RIPK), an RLCK VII subfamily member, contributes to ROS production in multiple layers of plant immune system.
2022年9月21日,国际权威 学术期刊 The Plant Cell 发表了 新西兰 植物与食品研究所有限公司Erik Rikkerink 团队的最新相关研究成果,题为 A conserved glutamate residue in RPM1-INTERACTING PROTEIN4 is ADP-ribosylated by the Pseudomonas effector AvrRpm2 to activate RPM1-...