pmc.ncbi.nlm.nih.gov
Molecular Subtype of Small Cell Lung Cancer - PMC
此外，Simpson等在患者循环肿瘤细胞来源模型（circulating-tumor-cell derived explant models）中识别出一个先前未报道的、高表达ATOH1的SCLC亚型，但该亚型的存在还需要在更 ...
sclc模型
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pmc.ncbi.nlm.nih.gov
Establishment of A Patient-derived Xenotransplantation ... - PMC
The SCLC PDX animal model and the chemoresistance PDX animal model have been successfully constructed, the success rate is 33%, which provides a platform for ...
aacrjournals.org
Development of a syngeneic mouse model to study small cell ...
Apr 21, 2025 ... Abstract. Small cell lung cancer (SCLC) is an aggressive neuroendocrine carcinoma with limited treatment options and a 5-year survival rate ...
www.sciencedirect.com
EP.06.50 Development of a Novel AI-Augmented Small Cell ...
Nucleai's baseline tumor H&E model was optimized for SCLC based on annotation of tumor, immune (including lymphocyte, granulocyte, macrophages), and stromal ...
pmc.ncbi.nlm.nih.gov
Research Progress on the Mechanism and Diagnostic ... - PMC
曾有学者总结了临床前模型在SCLC中的临床应用进展，并根据器官转移趋向性特点对转移相关的细胞表型及分子机制进行归纳后发现，上皮间质转化（epithelial ...
news.weill.cornell.edu
How One Type of Lung Cancer Can Transform into Another
Feb 8, 2024 ... ... (SCLC) that spreads rapidly and has few options for treatment. Researchers at Weill Cornell Medicine have developed a mouse model that ...
tlcr.amegroups.org
Tumor heterogeneity in small cell lung cancer defined and ...
SCLC, small cell lung cancer; GEMM, genetically engineered mouse model; PDX, patient-derived xenograft models; CTC, circulating tumor cell; CDX, CTC-derived ...
www.sciencedirect.com
A unique small cell lung carcinoma disease progression ...
SOX2, MYC and CD44 gradually enrich in an in vitro SCLC disease progression model. •. CSC marker increase correlated with colony formation potential and IR ...
www.frontiersin.org
A predictive model and mechanistic study of treatment ...
IntroductionExtensive-stage small cell lung cancer (ES-SCLC) is an aggressive malignancy with a poor prognosis. This study aimed to identify and validate ...
link.springer.com
Establishment of a small-cell lung cancer (SCLC) mouse ...
Mar 20, 2024 ... Establishment of a small-cell lung cancer (SCLC) mouse model using enhanced cancer stem-cell-functioning 3D SCLC spheroids. Original Article ...