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Jan 15, 2026 · Complete information for SOX10 gene (Protein Coding), SRY-Box Transcription Factor 10, including: function, proteins, disorders, pathways, orthologs, and expression.
The SOX10 gene belongs to a family of genes that plays a critical role in the formation of tissues and organs during embryonic development. Learn about this gene and related health conditions.
图1. 神经嵴细胞既表达SOX10，又表达SOX9；但，分化的神经胶质细胞和神经元则仅表达SOX9。 SOX10是神经嵴发育中的关键性转录因子，对于神经嵴祖细胞迁移中的存活及多能性（pluripotency）的维持非常重要。
Among these, SOX10, a member of the SOX gene family, stands out. Located on chromosome 22q13, the SOX10 gene encodes a transcription factor crucial for the differentiation, migration, and maintenance of tissues derive...
SOX10 and PAX3 interactions are thought to be regulators of other genes involved in the symptoms of Waardenburg syndrome, particularly MITF, which influences the development of melanocytes as well as neural crest formation.
Dec 19, 2024 · 本文详细介绍了SOX10基因的功能、作用机制及其在信号通路中的角色，以及与多种疾病的关系，帮助读者全面理解这一重要的转录因子基因。 什么是SOX10基因？ SOX10 （SRY-box transcription factor 10）是一个关键的转录因子，位于人类染色体22q13.1上。
Kuhlbrodt et al. (1998) cloned the rat SOX10 gene, which encodes a 466-amino acid protein with a molecular mass of approximately 50 kD. Northern blot analysis detected a 3-kb SOX10 mRNA transcript that was largely res...
