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It is also known by the surnames of the patients who were first found to manifest the defect (Stuart and Prower). Congenital Factor X deficiency is inherited as an autosomal recessive condition [1]. The exact frequenc...
该因子最初被称为Stuart-Prower因子，源于Stuart病例（FⅩ功能缺陷）与Prower病例（FⅩ合成缺如）的独立发现。后续研究揭示Stuart病例由FⅩ重链104位缬氨酸被蛋氨酸取代导致，而 上海瑞金医院 发现的11Ser→Arg突变为国际首报。
Coagulation factor X (EC 3.4.21.6), or Stuart factor, is an enzyme of the coagulation cascade, encoded in humans by F10 gene. [5] It is a serine endopeptidase (protease group S1, PA clan).
Explore symptoms, genetics, and treatments for Factor X deficiency (Stuart-Prower Factor deficiency). Learn about diagnosis, Coagadex®, and available therapies.
Apr 22, 2025 · Factor X is a protein that helps your blood clot. Learn about factor X deficiency, what causes it, what to expect, and more.
Apr 25, 2003 · The first two have been memorialized many times, but little has been said about Stuart Factor. The editors of the Journal of Thrombosis and Haemostasis are collecting stories about the discovery of the ...
本病最早报道于1956年，Hougie和Telfer分别报道1例名叫Stuart的男性病例和1例名叫Prower的女性病例。 故因子Ⅹ（FⅩ）又称为Stuart- Prower因子。 本病罕见，有人估计发病率低于1/50万。 （一）病因和发病机制 FⅩ缺乏症或FⅩ分子结构异常导致本病，后者又称FⅩ异常血症。
因子 IX：抗血友病因子 B、圣诞节因子 X因子：血栓激酶、血浆凝血活酶、Stuart因子, 斯图尔特-普罗尔因子因子 XI：抗血友病因子 C、血浆促血栓形成因子 C 因子XII：哈格曼因子、激活因子因子XIII：纤维蛋白稳定因子、纤维蛋白酶、转谷氨酰胺酶
Abstract Coagulation factor X (FX; synonyms: autoprothrombin III, Stuart–Prower factor) is a vitamin K-dependent glycoprotein that occupies a pivotal position in the coagulation cascade. After activation, activated FX...
Morawitz in 1905 may have been the first to isolate Factor X when he identified a factor named ‘thromboplastin’ that interacted with thrombogen to form thrombin. 1 In 1955, Duckert reported a factor deficiency distinc...
