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Jan 15, 2026 · TFRC is a gene that encodes a cell surface receptor for iron uptake and regulates erythropoiesis and neurologic development. Learn about its aliases, disorders, pathways, products, functions, expression...
TFR1的转录后水平主要由 IRP1 和 IRP2 调控，它们与TFR1 mRNA中的IRE结合来影响基因表达 [12-14]。 在翻译后水平，CD133（PROM1）是TFR1转运铁元素过程中的负调节因子，同时 EGF 受体、c- Abl 分子和 MARCH8 分子可能也参与其中。
Aug 19, 2025 · Gene target information for TFRC - transferrin receptor (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (PubMed: 26214738).
Transferrin receptor protein 1 (TfR1), also known as C luster of D ifferentiation 71 (CD71), is a protein that in humans is encoded by the TFRCgene. [5][6] TfR1 is required for iron import from transferrin into cells ...
Oct 23, 2024 · 本文介绍了转铁蛋白受体TFR1（TFRC）是一种调节细胞内铁代谢的重要膜蛋白，与贫血、神经退行性疾病、癌症等多种疾病有关。文章还介绍了TFR1的临床研究进展和华美生物提供的TFR1相关产品。
转铁蛋白受体： 该基因编码细胞表面受体，该受体是通过受体介导的内吞作用过程摄取细胞铁所必需的。 该受体是红细胞生成和神经系统发育所必需的。 已识别出多个可变剪接变体。 [RefSeq 提供，2015 年 9 月]
